Anti-Diabetic Effect of Quercetin to Reduce Blood Sugar Levels
Known as a flavonoid it's found in many plants and foods, such as red wine, onions, green tea, apples and berries. It’s one of the most abundant antioxidants in our diet and plays an important role in helping your body to combat free radical damage, which is linked to chronic diseases and DNA damage. Free radicals are unstable molecules that may cause cellular damage when their levels become too high 1.
What are the benefits of Quercetin?
- Boost immunity
- Fight inflammation
- Combat allergies
- Aid exercise performance
- And maintain general health
Quercetin is most commonly used for conditions of the heart and blood vessels and to prevent cancer. It is also used for arthritis, bladder infections, and diabetes.
Where can I find natural Quercetin in food?
What foods are rich in Quercetin?
These commonly eaten foods are good sources of Quercetin:
- Cherry Tomatoes
Blueberries are antioxidant superstars. On top of Quercetin, they contain 17 different phytochemicals including resveratrol, the healthy antioxidant best known for appearing in red wine.
Apples contain four different phytochemicals along with the beneficial fiber known as pectin. To get the benefits of Quercetin, eat your apples unpeeled. Remember, apple juice doesn’t provide the same benefits as the whole fruit.
How does Quercetin help to reduce blood sugar levels?
Does Quercetin help improve blood sugar levels?
Diabetes is the most common serious metabolic disorder and it is one of the five leading causes of death worldwide. It is characterized by persistent high levels of blood sugar known as hyperglycemia associated with carbohydrate, protein, and lipid metabolism abnormalities 4. Currently, 171 million people are affected with diabetes and the number is expected to rise to 366 million by 2030 5. This disease is caused by a decrease or deficiency in insulin secretion and increased cellular resistance to insulin which plays a role in regulating blood sugar levels and availability to the cells.
Along with the induction of oxidative stress 6 and alterations in glucose and lipid metabolism-regulating enzymes. Controlling of blood glucose level is essential for preventing diabetic complications and improving the health of patients with diabetes 7.
Quercetin and resveratrol, two structurally-related flavonoids, are naturally occurring phenolic compounds that are widely distributed in plants and natural foods and are reported to have many beneficial effects including anti-inflammatory, anti-oxidative, anti-hypertensive, anticancer, antiviral, neuroprotective, hepatoprotective and anti-diabetic activities.
Quercetin is also taken to help against Type 2 diabetes and its complications. Quercetin showed similar effects as that of metformin which is a widely prescribed antidiabetic drug in cell lines models. In vivo it looks to be a promising agent against diabetes.
Quercetin stimulates cellular glucose uptake in the cells and decreases a rise in your blood sugar. It regulates key signaling pathways involved in glucose metabolism. Reducing oxidative stress and improving insulin resistance, its use is promising against the complications of diabetes.
How much Quercetin should I take?
Quercetin has most often been used by adults in doses of 250-1000 mg taken orally. The most common oral dosage is Quercetin 500mg twice a day and some take one 500mg capsule once a day for a desired effect. Optimal doses of Quercetin have not been established for any particular condition.
Where can I buy Quercetin?
Where is it available?
You can buy Quercetin organic capsules supplements on Amazon, Walmart, eBay or other online retailers. On Amazon here are our some top Quercetin choices
- BoostCeuticals Quercetin 500mg - 200 capsules per bottle for $34.99, which is also vegan with no artificial additives or fillers and potentially harmful stearates
- Jarrow Formulas Quercetin 500 mg - 200 capsules per bottle for $40.41
- Forest Leaf Quercetin 500mg - 180 capsules per bottle for $39.95
In summary, Quercetin is the most abundant dietary flavonoid. It has been linked to improved exercise performance and reduced inflammation, healthy blood pressure and blood sugar levels. Plus, it may have brain-protective, anti-allergy, and anticancer properties. For a measured dosage difficult to obtain from the diet alone Quercetin capsules are a popular choice.
- Evolution of the Knowledge of Free Radicals and Other Oxidants
- Free, radicals, antioxidants in disease and health
- Ramesh B, Pugalendi KV. Antihyperglycemic effect of umbelliferone in streptozotocin-diabetic rats. J Med Food. 2006;9:562–566. doi: 10.1089/jmf.2006.9.562.
- Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care. 2004;27:1047–1053. doi: 10.2337/diacare.27.5.1047.
- Machha A, Achike FI, Mustafa AM, Mustafa MR. Quercetin, a flavonoid antioxidant, modulates endothelium-derived nitric oxide bioavailability in diabetic rat aortas. Nitric Oxide. 2007;16:442–447. doi: 10.1016/j.niox.2007.04.001.
- Ceriello A. Postprandial hyperglycemia and diabetes complications: is it time to treat? Diabetes. 2005;54:1–7. doi: 10.2337/diabetes.54.1.1.
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